The Integration of Bioinformatics into a Biology Curriculum


Sequencing microbes as a method of developing core bioinformatics skills while learning basic principles in microbiology, genetics, ecology and evolution.

Goal:  To engage large numbers of undergraduate students in authentic scientific discovery using modern tools of genetics and bioinformatics.  The specific experience involves the culturing of microbes and their characterization by genome sequencing.

Course Outline

  • Microbiology
  • Molecular Biology
    • Extract DNA using a standard kit
    • Submit DNA sample to the NH-INBRE core (HCGS).
    • You receive a “Big Data” file of sequences for each student’s sample
  • Bioinformatics
    • Establish fundamental BASH/Command line skills
    • Walk through the steps of analysis.
    • Data QC_Genome Assembly_Genome Annotation_Genome Comparison


The NH-INBRE Bioinformatics Core Provides:

  • Step by step active learning video tutorials.
  • Instructor support and testing materials.
  • The platform (server), so you won’t need to purchase or maintain one on site.
  • Sequencing of data.
  • Online support.


For faculty interested in exploring this curriculum please download the following Guide.
Teaching Guide: NH-INBRE Bioinformatics Course Curriculum.
Command Line Introduction
Devin Thomas and Jordan Ramsdell,
Hubbard Center for Genome Studies, University of New Hampshire,
Durham NH 03824

Access Tutorials Here