Research supported by NH-INBRE

All of the NH-INBRE Goals are strongly supported by the Developmental Research Projects Program (DRPP), which funds competitive cutting-edge biomedical research proposed and led by faculty at Partner institutions that enables intense engagement by both students and faculty at Partners.

NH-INBRE funding establishes research programs that successfully compete for other funding sources as the research develops.

 

Research projects are of three types:

(1) Research Projects require a 50% effort commitment from the faculty principal investigator.

(2) Pilot Projects require a 25% effort commitment from the faculty principal investigator.

(3) Collaborative Projects are Research or Pilot Projects that include a collaborating faculty member from Dartmouth or UNH.

 

 

Current Research Projects (7/1/2018 – 6/30/2020)

COLLABORATIVE PILOT PROJECT

Paul Baures, Keene State College
Advancement of a novel fatty acid synthase inhibitor
Collaborator and Mentor: William Kinlaw, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Michael Brian, Plymouth State University
Effects of varying intensity exercise on glycemic control & blood pressure regulation in sedentary young
adults at-risk for Metabolic Syndrome.
Mentors: Sushela Chaidarun and Mark Craeger, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Heather Doherty, Plymouth State University
Detection of CTGF SNPs and correlation to clinical variables in the Framingham Heart Study Omni Cohort 1
Mentor: Brock Christensen and John Batsis, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Harlan Fichtenholtz, Keene State College
Neural Mechanisms of Emotional Vigilance in Posttraumatic Stress Disorder (PTSD)
Mentors: Matthew Friedman, Geisel School of Medicine at Dartmouth and Kevin Fleming, Norwich University

PILOT PROJECT

Leila Jabbour, Franklin Pierce University
Expression Pattern of △FosB in Human Post Mortem Tissue from Opioid Overdose
Mentor: Kyle Smith, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Kristen Johnson, University of New Hampshire – Manchester
Studying the impact of altered gene expression in pancreatic cancer cells using CRISPRa/i
Mentor: Steven Leach, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Deborah McCarter, Saint Anselm College
Enhancing follow-up mechanisms for women at risk for postpartum depression
Mentor: Mark Hegel, Geisel School of Medicine at Dartmouth

COLLABORATIVE PILOT PROJECT

Kyle MacLea, University of New Hampshire – Manchester
Factors Affecting the Propagation of [PSI+] Prions in Saccharomyces cerevisiae
Collaborator: Linda Coe, Great Bay Community College
Mentors: Surachai Supattapone and Charlie Barlowe, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Priyanka Roy Chowdhury, Keene State College
Role of Nutritional Status on Arsenic Susceptibility
Mentors: Brian Jackson and Kate Buckman, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Daniel Seichepine, University of New Hampshire – Manchester
Effects of Parkinson’s disease subtype on executive function and personality attributes
Mentor: Stephen Lee, Geisel School of Medicine at Dartmouth

 

Previous Research Projects

COLLABORATIVE PILOT PROJECT

Paul Baures, Keene State College
Advancement of a novel fatty acid synthase inhibitor
Collaborator and Mentor: William Kinlaw, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Michael Brian, Plymouth State University
Glycemic control and blood pressure assessments in obese young adults

PILOT PROJECT

Heather Doherty, Plymouth State University
Detection of CTGF SNPs and correlation to clinical variables in the Framingham Heart Study Omni Cohort 1
Mentor: Brock Christensen, Geisel School of Medicine at Dartmouth

COLLABORATIVE PILOT PROJECT

Harlan Fichtenholtz, Keene State College
Neural Mechanisms of Emotional Vigilance in Posttraumatic Stress Disorder (PTSD)
Collaborator and Mentor:Lauren Sippel, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Leila Jabbour, Franklin Pierce University
Expression Pattern of △FosB in Human Post Mortem Tissue from Opioid Overdose

PILOT PROJECT

Kristen Johnson, University of New Hampshire – Manchester
Studying the impact of altered gene expression in pancreatic cancer cells using CRISPRa/i
Mentor: Steven Leach, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Deborah McCarter, Saint Anselm College
Enhancing follow-up mechanisms for women at risk for postpartum depression
Mentor: Mark Hegel, Geisel School of Medicine at Dartmouth

COLLABORATIVE PILOT PROJECT

Kyle MacLea, University of New Hampshire – Manchester
Factors Affecting the Propagation of [PSI+] Prions in Saccharomyces cerevisiae
Collaborator: Deborah Audino, Great Bay Community College

PILOT PROJECT

Priyanka Roy Chowdhury, Keene State College
Role of Nutritional Status on Arsenic Susceptibility

PILOT PROJECT

Daniel Seichepine, University of New Hampshire – Manchester
Effects of Parkinson’s disease subtype on executive function and personality attributes

COLLABORATIVE PILOT PROJECT

Lori Bergeron, New England College

C-di-GMP mediated biofilm formation in Pseudomonas fluorescens

Collaborator and Mentor: George O’Toole, Geisel School of Medicine at Dartmouth

COLLABORATIVE PILOT PROJECT

Chris Chabot, Plymouth State University

Molecular and cellular mechanisms of circadian and circatidal rhythms

Collaborator and Mentor: Winsor Watson, University of New Hampshire

COLLABORATIVE PILOT PROJECT

Paul Baures, Keene State College

Advancement of a novel fatty acid synthase inhibitor

Collaborator and Mentor: William Kinlaw, Geisel School of Medicine at Dartmouth

COLLABORATIVE PILOT PROJECT

Anthony Scioli, Keene State College

An efficacy and feasibility study of a hope-centered intervention for adolescents

Collaborator and Mentor: Anna Adachi-Mejia, Geisel School of Medicine at Dartmouth

COLLABORATIVE PROJECT

James Newcomb, New England College

Neural mechanisms of circadian rhythms and interactions between clocks

Collaborator and Mentor: Winsor Watson, University of New Hampshire

RESEARCH PROJECT

Mike Son, Plymouth State University

The effects of clinically relevant SNPs on virulence capabilities of V. cholerae

Mentor: Deborah Hogan, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Daniel Broek, Saint Anselm College

Cell survival through a dicentric chromosome phase

Mentor: Duane Compton, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Deborah McCarter-Spaulding, Saint Anselm College

Enhancing follow-up mechanisms for women at risk for postpartum depression

PILOT PROJECT

Amy Piispanen, Franklin Pierce University

Regulation of the Cek1 MAP kinase cascade and morphogenesis in Candida albicans

Mentor: Paula Sundstrom, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Thomas Shell, Saint Anselm College

Targeted treatment of cancer and neurological disorders

PILOT PROJECT

Lawrence Welkowitz, Keene State College

Behavioral and cortical effects of computerized language training for autism

COLLABORATIVE PILOT PROJECT

Lori Bergeron, New England College

Metal dependent gene expression in A. naeslundii

Collaborator and Mentor: George O’Toole, Geisel School of Medicine at Dartmouth

COLLABORATIVE PILOT PROJECT

James Newcomb, New England College

Molecular & neural mechanisms of circadian rhythms in a gastropod model organism

Collaborator and Mentor: Winsor Watson, University of New Hampshire

RESEARCH PROJECT

Daniel Broek, Saint Anselm College

A yeast-based screen for identification of mammalian genes that regulate ploidy

Mentor: Duane Compton, Geisel School of Medicine at Dartmouth

RESEARCH PROJECT

Chris Chabot, Plymouth State University

Molecular and cellular mechanisms of circadian and circatidal rhythms

Mentor: Winsor Watson, University of New Hampshire

COLLABORATIVE PROJECT

Susan Whittemore, Keene State College

Identification of signaling pathways affected by early exposure to prevalent PAHs

Collaborator and Mentor: Leslie Henderson, Geisel School of Medicine at Dartmouth

COLLABORATIVE PILOT PROJECT

Susan Arruda, Franklin Pierce University

Characterizing a novel G protein-coupled receptor in Drosophila vision

Collaborator and Mentor: Patrick Dolph, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Marjorie King, Plymouth State University

Reliability of center of foot pressure in the older adult population

Mentor: Jon Lurie, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Mike Son, Plymouth State University

Characterization of increased virulence mechanisms in clinical V. cholerae

Mentor: Deborah Hogan, Geisel School of Medicine at Dartmouth

PILOT PROJECT

James Jukosky, Colby-Sawyer College

Developing novel antimicrobials derived from burying beetles

Mentor: Steven Fiering, Geisel School of Medicine at Dartmouth

PILOT PROJECT

Jason Pellettieri, Keene State College

Light-induced pigment cell apoptosis

Mentor: David Mullins, Geisel School of Medicine at Dartmouth 

COLLABORATIVE PROJECT

Nicholas Baer, Colby Sawyer

The role of ecological, chemical and landscape factors in determining methyl mercury bioaccumulation in stream food webs

Collaborator: Celia Chen, Geisel School of Medicine at Dartmouth

COLLABORATIVE PROJECT

Adam Wenzel, Saint Anselm College

The influence of body mass index on changes in macular pigment, serum carotenoids and c-reactive protein

Collaborator: Joanne Curran Celentano, University of New Hampshire

PILOT PROJECT

Heather Frasier Chabot, New England College

Health and its association with physiologic distress and bystander intervention in domestic violence     

PILOT PROJECT

Loren Launen, Keene State College

A molecular characterization of the structure and function of aromatic hydrocarbon degrading microbes present in the tidal wetlands of the Great Bay estuary     

PILOT PROJECT

Bill Thomas, Colby-Sawyer College

An analysis of a-catenin functions in transfected DLC1 carcinoma cells       

PILOT PROJECT

Joseph Troisi, Saint Anselm College

Pavlovian and operant interactions of discriminant stimulus effects of nicotine and ETOH in rats: Analyses of conditioned reinforcement, extinction, and response recovery

 

McCarter-Spaulding Lab at Saint Anselm College
From left, Sheila Trifone, Keerstyn Allen, Hannah Pirozzoli, Felicia McKinnon, and Professor Deborah McCarter-Spaulding, Ph.D., WHNP-BC, RN

 

Students from the Bergeron and Newcomb Labs at New England College
From left to right, Thomas Lott, David Giacalone, Kaitlin Warwicker, Emily Gubbins, Rachel Thomas, and Izhar Mbarani.

 

Baures lab at Keene State College
From left to right: Mallory Pearce, Evan Dunkley, Margaret Maloy, Paul Baures, Ph.D., Elizabeth McGurk, and Victoria Smolenski.